21 Night Cruise sailing from San Francisco to New York aboard Seven Seas Navigator.

In the six-star tradition of Regent Seven Seas Cruises, the Seven Seas Navigator is destined for distinction. Occupying the uppermost niche in cruising, she offers her 490 guests an unusual level of luxury and some of the highest space and service ratios at sea. From her all-suite, all-ocean-view accommodations with their luxurious marble baths to her signature cuisine to her superbly attentive staff, she has few equals.

Highlights of this cruise:

San Francisco
From the first Spanish Mission founded by the "Sacred Expedition" in 1776, to the rip-roaring days of the Barbary Coast and California Gold Rush to rising phoenix-like after the great earthquake of 1906, San Francisco never ceases to please the eye, the heart and the palate. With such iconic sites as Chinatown, Golden Gate Bridge, Alcatraz, Fisherman's Wharf, the Victorian architecture of Pacific Heights, Union Square, colorful trolley cars, Muir Woods and the surrounding vineyards of Napa and Sonoma Valley, the "City by the Bay" is always a must-see on any visitor's list to the West Coast.

Cabo San Lucas
Twenty years ago Cabo San Lucas, at the southernmost tip of Baja, was little more than a fishing village occasionally visited by itinerant Californian surfers and sport fishermen with the means to sail in or fly down. In recent years, however, it has rapidly become the focal point of Los Cabos, the catch-all term for the beaches and resorts ringing the toe of the peninsula. Condos have sprung up, palms transplanted, water piped in and everything is kept pristine.

Acapulco
Acapulco, nicknamed "Pearl of the Pacific," is Mexico's most glamorous pacific resort. Located on a deep, semi-circular bay, Acapulco is located southwest of Mexico City. Few destinations can match its superb weather with an average of 360 days of sunshine per year and with temperatures comfortably in the 80s. Acapulco was important as a port city for Spanish galleons sailing between Spain and the Orient long before it was "discovered" as a vacation playground.

Huatulco
Huatulco is located in the southern part of the state of Oaxaca. This newly-developed resort area is near the village of Puerto Escondido. The area has nine bays with beautiful beaches, among the cleanest, safest and least crowded on the west coast. Huatulco is targeted for development as a major tourist destination, but with an eye to environmental protection. The government dictates only 5% of the area can be developed in order to keep with ecological regulations.

Puntarenas
Puntarenas, which means "Sandy Point" in Spanish, is the capital and main city in the province Puntarenas, Costa Rica, at the Pacific coast. The oddly-shaped province has its largest section in the South, far from the capital. A mountainous country, Costa Rica ranges from sea level to peaks as high as 13,000 feet and a succession of white, sandy beaches follow one another along the Pacific Coast. The country was discovered by Christopher Columbus in 1502.

Cartagena
Take a scenic drive through the residential area of Manga, and admire the beautiful mansions built in Republican-style architecture at the end of the 19th century. Explore the Castillo San Felipe de Barajas, a fort that was once the most important military structure built in Latin America. Enjoy a boat ride to the Islas del Rosario, 26 coral islands located off the coast of Isla Baru, and continue to the island of San Martin de Pajarales to visit the aquarium. Enjoy a spectacular dolphin and shark show and other marine attractions there. Board the beautiful Spanish Galleon, a replica of a 17th-century sailing ship, for a cruise of the inner bay of Cartagena.

Grand Cayman
Christopher Columbus discovered the Cayman Islands in 1503 and named them Las Tortugas, because the only inhabitants found were turtles. By 1530, they were known as the Caymanas, meaning "crocodile" in Carib. Although Sir Francis Drake visited the islands in 1568, they did not come under British rule until 1670. The Caymanians are descendants of the English, Irish, Scottish and Welsh seamen who settled the islands and later intermarried with Jamaican immigrants.

Ft Lauderdale
Fort Lauderdale sits in the middle of the burgeoning megalopolis of South Florida, which hugs the Atlantic coast from Miami in the south (a 35-minute car ride away) to Palm Beach in the north. In the city limits alone, there are more than 165 miles of navigable waterways, and more than 42,000 registered yachts. Downtown Fort Lauderdale is peppered with high-rise buildings, sidewalk cafes, bars and shops, creating the perfect location for people-watching!

New York
The 'City that Never Sleeps' beckons - renowned museums and sites galore by day; the glittering sophistication of clubs, theaters and restaurants by night. Explore Chinatown, Greenwich Village, the United Nations, Central Park's Museum Mile and Wall Street's towering steel and glass monuments to commerce, then hop into a cab for an afternoon of world-class shopping along Park and Fifth Avenues.